What are Biomarkers?

Understanding Biomarkers: Your Health’s Informative Indicators
Introduction to Biomarkers

Biomarkers are measurable indicators found in your body that provide important information about your health. They help to diagnose diseases, monitor how well treatments are working, and predict future health risks. There are two main types of biomarkers:
Substances Found in the Body
Snapshot Biomarkers: These are measured once and provide a snapshot of your current health. They can be divided into two types:
Short-Lived Biomarkers: These reflect your recent habits and diet over the past few days, such as triglyceride levels, which indicate the fat content of your most recent meals.
Long-Term Biomarkers: These indicate the long-term impact of your health habits. For example, Hemoglobin A1c shows how your body utilizes glucose and reflects your average glucose levels over the past six months. Another example is the anti-mullerian hormone, which reflects overall biological age in women.
Besides blood and urine tests, other bodily tests measure biochemical products in the body to give insights into your health. Examples include stool tests that analyze the gut microbiome and breath tests that detect H. pylori, an important microbe in the GI disorder cascade.
Dynamic Bioparameters
These biomarkers provide a more precise and accurate picture of your health, pinpointing areas that need improvement for better health. Examples include:
Fat and Muscle Body Composition
Bone Density
VO2 Max (a measure of cardiovascular fitness)
Glucose Variability
Blood Pressure Variability
Percentage of Arrhythmic Episodes
Microvascular Health (capillary network in every organ related to mitochondrial and DNA health)
By tracking these biomarkers, you can get a comprehensive understanding of your overall health and take proactive steps to improve it, thereby preventing serious health issues that may require medication.
Making Biomarkers Actionable
The most prominent feature of tracking biomarkers is that once you have the values from your blood tests, you can match them to certain habits or aspects of your daily life, making it visible and actionable for improvement. For example, low energy is often associated with a pre-diabetic physiological profile that fits specific blood test results (high insulin levels, high blood sugar variations, and above 90 mg/dl morning glucose).
When you observe that the amount and timing of your food intake impact your minute-to-minute glucose levels, which are closely tied to your feelings of fatigue and low energy, you can address these specific issues. By decreasing the intake of specific foods, such as certain fruits, or having 2 meals per day instead of 4-5, you can significantly improve your energy levels. As a result, your symptoms of low energy disappear along with improved bioparameters.
Importance of Blood Work
Blood work gives us an understanding of your essential nutrients, thyroid function, cardiovascular health, metabolic functioning, inflammatory markers, hormones, biological age, and more. Most physicians focus only on values outside the normal ranges and often ignore the early trends connected to symptoms within the normal range.
Waiting for a blood bioparameter value to fall outside the normal range is often too late to make meaningful changes and prevent disease, leading to prescribed medications with potential side effects. A deep understanding of the values and detecting early trends associated with habits identified on the dynamic scan is critical to maintaining vibrant health.
Holistic Approach to Health
Looking at everything in the body—all tissues, organs, and their functions—simultaneously is paramount to addressing a symptom or complaint. In the body, everything is connected like a finely tuned clock mechanism. For example, if there are signs of prediabetes with insulin resistance and weight gain, not addressing liver function and microcirculation with optimal mitochondrial function would lead to the failure of any treatment.
Understanding these connections allows for a complete and successful approach to health, ensuring that non-invasive (meds-free) interventions are timely and effective.
Blood Bioparameters and Their Associations
Below are examples of blood bioparameters associated with specific organs and tissues:
Liver Function Tests: These include ALT, AST, and bilirubin levels, indicating liver health.
Kidney Function Tests: These include creatinine and BUN levels, reflecting kidney health.
Cardiovascular Health Markers: These include cholesterol levels (HDL, LDL, and total cholesterol) and triglycerides.
Inflammatory Markers: These include CRP (C-reactive protein) and ESR (erythrocyte sedimentation rate).
Hormonal Profiles: These include thyroid hormones (TSH, T3, T4) and sex hormones (estrogen, testosterone).
By analyzing these biomarkers, VitalSight can develop a precise, methodical plan to address health issues and optimize your overall well-being.
Conclusion
The bottom line is that biomarker values are arbitrary unless they are tied to you and something you can address. With VitalSight, the problem of stubborn weight gain, low energy, anxiety, and other health issues becomes a math equation that is solved in a precise, methodical way. By identifying the causes and strategically working towards the goal, you can achieve optimal health and vitality.

Heart and Vascular Health

  • Apolipoprotein B (ApoB)
  • Cholesterol / HDL Ratio 
  • HDL Cholesterol 
  • HDL Large
  • LDL Cholesterol 
  • LDL Medium
  • LDL Particle Number
  • LDL Pattern
  • LDL Peak Size
  • LDL Small
  • Lipoprotein (a)
  • Lipoprotein Fractionation
  • Non-HDL Cholesterol 
  • Total Cholesterol 
  • Triglycerides 
  • High-Sensitivity C-Reactive Protein (hsCRP) 

Thyroid Function

  • Thyroglobulin Antibodies (TgAb)
  • Thyroid Peroxidase Antibodies (TPO)
  • Thyroid-Stimulating Hormone (TSH)
  • Thyroxine (T4) Free
  • Triiodothyronine (T3) Free
  • Iodine 
  • Selenium 

Cancer Detection

  • Multi-Cancer Detection Test 
  • Prostate Specific Antigen (PSA), Free
  • Prostate Specific Antigen (PSA), Total
  • Prostate Specific Antigen (PSA) % Free

Autoimmunity

  • Antinuclear Antibodies (ANA) Screen
  • Antinuclear Antibodies (ANA) Pattern
  • Antinuclear Antibodies (ANA) Titer
  • Celiac Disease (Comprehensive Panel)
  • Rheumatoid Factor

Immune Regulation

  • High-Sensitivity C-Reactive Protein (hsCRP) 
  • White Blood Cell Count (WBC) 
  • Neutrophils
  • Lymphocytes 
  • Monocytes 
  • Eosinophils 
  • Basophils 
  • Lyme Disease Antibodies 

Female Health

  • Anti-Mullerian Hormone
  • Estradiol (E2)
  • Follicle Stimulating Hormone (FSH)
  • Luteinizing Hormone (LH)
  • Progesterone
  • Prolactin
  • Testosterone, Free (female)
  • Testosterone, Total
  • Sex Hormone Binding Globulin (SHBG)
  • DHEA-Sulfate (female)

Male Health

  • DHEA-Sulfate (male)
  • Estradiol (E2) (male)
  • Follicle Stimulating Hormone (FSH) (male)
  • Luteinizing Hormone (LH)
  • Prostate Specific Antigen (PSA), Free
  • Prostate Specific Antigen (PSA), Total
  • Prolactin (male)
  • Sex Hormone Binding Globulin (SHBG)
  • Testosterone, Total
  • Testosterone, Free (male)

Metabolic Health

  • Adiponectin 
  • Glucose 
  • Hemoglobin A1c (HbA1c) 
  • Insulin 
  • Leptin
  • Uric Acid

Nutrient Levels

  • Arachidonic Acid/EPA Ratio
  • Copper 
  • Ferritin
  • Homocysteine
  • Iron
  • Iron % Saturation
  • Iron Binding Capacity (TIBC)
  • Magnesium
  • Methylmalonic Acid (MMA)
  • Omega-3 Total
  • Omega-3: EPA+DPA+DHA
  • Omega-6 Total
  • Omega-6: Arachidonic Acid
  • Omega-6: Linoleic Acid
  • Omega-6 / Omega-3 Ratio
  • Selenium 
  • Vitamin D
  • Zinc

Liver Function

  • Alanine Transaminase (ALT) 
  • Albumin 
  • Alkaline Phosphatase (ALP) 
  • Aspartate Transaminase (AST) 
  • Gamma-glutamyl Transferase (GGT)
  • Total Bilirubin 
  • Total Protein 

Kidney Function

  • Albumin (Microalbumin) – Urine
  • Blood Urea Nitrogen (BUN)
  • BUN / Creatinine Ratio 
  • Calcium 
  • Chloride 
  • Creatinine 
  • Estimated Glomerular Filtration Rate (eGFR) 
  • Globulin 
  • Potassium 
  • Sodium 

Pancreas Function

  • Amylase
  • Lipase

Heavy Metals

  • Aluminum 
  • Arsenic 
  • Lead
  • Mercury

Blood Health

  • ABO Group and Rhesus (Rh) Factor
  • Hematocrit 
  • Hemoglobin 
  • Mean Corpuscular Hemoglobin (MCH)
  • Mean Corpuscular Hemoglobin Concentration (MCHC)
  • Mean Corpuscular Volume (MCV) 
  • Mean Platelet Volume (MPV)
  • Platelet Count 
  • Red Blood Cell (RBC) Count
  • Red Cell Distribution Width (RDW) 

Electrolytes

  • Calcium 
  • Magnesium, RBC
  • Sodium 
  • Chloride 
  • Potassium 
  • Carbon Dioxide 

Urine Analysis

  • Albumin – Urine (Microalbumin)
  • Appearance 
  • Bacteria 
  • Bilirubin 
  • Clarity 
  • Color 
  • Creatinine – Urine
  • Glucose-Urine 
  • Hyaline Casts 
  • Ketones 
  • Leukocytes 
  • Nitrite 
  • Occult Blood 
  • pH 
  • Protein 
  • Red Blood Cell 
  • Specific Gravity 
  • Squamous Epithelial Cells 
  • White Blood Cell (WBC) 
  • Yeast 

Alzheimer’s Risk

  • Apolipoprotein E (ApoE) Genotype 

Allergies

  • Food Allergy Profile (IgE) 
  • Indoor & Outdoor Allergy Profile (IgE) 

Sexual Health

  • Chlamydia 
  • Gonorrhea
  • Herpes Simplex Virus 1 and 2 
  • HIV 1 & 2 Antigen-Antibody 
  • Trichomoniasis
  • RPR (Syphilis) 

Stress & Aging

  • Cortisol
  • DHEA-Sulfate (female)
  • Biological Age 
  • Insulin-like Growth Factor (IGF-1) 

Dynamic Testing

Dynamic Testing with the Medical Grade Device 

Our dynamic testing records every heartbeat, muscle movement, and provides detailed insights into cellular health at the deepest level. This advanced testing includes:

Balanced Autonomic Nervous System Having just enough “good stress” and the right amount of recovery for proper digestion and renewal is something difficult to figure out on your own, especially when being pulled by work, family, and social obligations. Objective and accurate assessment with Heart Rate Variability Array, oxygen consumption, and glucose variability gives a map of how your brain organizes the day and uses body resources. Almost like an Excel balance sheet, you can see for yourself what is good, bad, and ugly.

Heart Health

  • Electrocardiogram (ECG): Continuous 2-lead ECG records the electrical activity of the heart to detect abnormalities.

Muscle Health

  • Muscle Movement Analysis: Tracks muscle activity to evaluate strength, function, and efficiency.

Cellular Health Analysis Provides a comprehensive view of cellular function and overall health.

This sophisticated approach allows for continuous monitoring and precise adjustments to your health plan, ensuring the best health outcomes.